TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE
TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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LabCyteCORNEAMODEL24 eye irritation test
TM Status: Closed
Test Method Number: TM2015-04 (JAP)
Short Name of TM: LabCyteCORNEAMODEL24 EIT
Responsible Organisation: JaCVAM - Japan
Topic(s): Serious eye damage/Eye irritation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Thyroid method 2b: Thyroperoxidase (TPO) inhibition based on oxidation of Luminol
TM Status: Open
Test Method Number: TM2019-05 (EU)
Short Name of TM: TPO-LUM
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Thyroid method 8b: Proliferation, migration and oligodendrocyte maturation (including myelin formation) in mixed neuronal/glial culture (neurospheres) derived from human induced Pluripotent Stem Cells (hiPSC)
TM Status: Open
Test Method Number: TM2019-18 (EU)
Short Name of TM: PMOD-hNPC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
In vitro model for the prediction of respiratory sensitization of inhalable substances
TM Status: Closed
Test Method Number: TM2019-01 (EU)
Short Name of TM: ALIsens
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Two-tiered approach to determine the skin sensitising capacity and potency of chemicals
TM Status: Closed
Test Method Number: TM2011-12 (EU)
Short Name of TM: 2-TA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards