TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE
TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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In Vitro Skin Sensitisation: The FBS free ARE-Nrf2 Luciferase α-Sens® Test Method
TM Status: Open
Test Method Number: TM2022-03 (JAP)
Short Name of TM: α-Sens®
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin sensitisation
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    Submission
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    Validation
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    Peer-review
  •  
    Recommendation
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    Regulatory acceptance/Standards
Lung Surfactant Bioassay
TM Status: Open
Test Method Number: TM2026-01 (EU)
Short Name of TM: LS Bioassay
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Acute toxicity,
Human Health Effects
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Quantitative prediction of inflammation from acute to chronic condition associated with inhalation and delivered ahead of time by lung animal-free in-vitro-learned digital twin (InFiniteLungDT)
TM Status: Closed
Test Method Number: TM2025-02 (EU)
Short Name of TM: InFiniteLungDT
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Human Health Effects
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    Submission
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    Validation
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    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Thyroid method 2c: Tyrosine iodination using liquid chromatography
TM Status: Closed
Test Method Number: TM2019-06 (EU)
Short Name of TM: TYRO-IOD
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
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    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Thyroid receptor microarray assay for real-time Nuclear Receptor-coregulator interaction
TM Status: Closed
Test Method Number: TM2017-02 (EU)
Short Name of TM: TR MARCoNI
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards