TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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Murine Local Lymph Node Assay
TM Status: Closed
Test Method Number: TM1998-05 (US)
Short Name of TM: Murine Local Lymph Node Assay
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Sensitisation
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    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Ros (Reactive Oxygen Species) Assay for Photoreactivity
TM Status: Closed
Test Method Number: TM2013-04 (JAP)
Short Name of TM: Ros Assay
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin irritation,
Skin sensitisation,
Genotoxicity/Mutagenicity
  •  
    Submission
  •  
    Validation
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    Peer-review
  •  
    Recommendation
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    Regulatory acceptance/Standards
IL-8 Luciferase assay for skin sensitization
TM Status: Closed
Test Method Number: TM2016-10 (JAP)
Short Name of TM: IL-8 Luciferase assay for skin sensitization
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin sensitisation
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    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Vitrigel-Eye Irritancy Test
TM Status: Closed
Test Method Number: TM2011-15 (JAP)
Short Name of TM: Vitrigel-Eye Irritancy Test
Responsible Organisation: JaCVAM - Japan
Topic(s): Serious eye damage/Eye irritation
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    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Androgen Receptor TransActivation Assay using the stably transfected human AR-EcoScreen™ cell line
TM Status: Closed
Test Method Number: TM2012-07 (JAP)
Short Name of TM: AR-Ecoscreen test
Responsible Organisation: JaCVAM - Japan
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards