TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE
TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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Androgen Receptor TransActivation Assay using the stably transfected human AR-EcoScreen™ cell line
TM Status: Closed
Test Method Number: TM2012-07 (JAP)
Short Name of TM: AR-Ecoscreen test
Responsible Organisation: JaCVAM - Japan
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Stably Transfected Human Estrogen Receptor-α Transactivation Assay using the (h) ERα-HeLa-9903 cell line
TM Status: Closed
Test Method Number: TM2008-17 (JAP)
Short Name of TM: ER-STTA assay
Responsible Organisation: JaCVAM - Japan
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
In Chemico Skin Sensitisation: Amino acid Derivative Reactivity Assay
TM Status: Closed
Test Method Number: TM2016-12 (JAP)
Short Name of TM: ADRA for skin sensitization
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
LabCyte EPI-MODEL24 skin irritation test
TM Status: Closed
Test Method Number: TM2008-14 (JAP)
Short Name of TM: LabCyte EPI-MODEL24 SIT
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin irritation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
LabCyte EPI-MODEL24 skin corrosion test
TM Status: Closed
Test Method Number: TM2017-03 (JAP)
Short Name of TM: LabCyte EPI-MODEL24 SCT
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin Corrosion
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards