TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

Note that TSAR includes only the methods that have been validated by governmental organisations affiliated with the International Cooperation on Alternative Test Methods (ICATM).

Furthermore, the documentation included in the TSAR database are the versions that were used during the validation of the respective test methods. These documents are provided for reference and transparency purposes only and may not correspond to the most up-to-date versions currently in use, nor can it be excluded that additional documentation exists. For the latest SOPs and technical information, users should contact the relevant test method developer.

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Dendritic Cell Migration Assay for distinguishing sensitizers from non-sensitizers (including irritants)
TM Status: Closed
Test Method Number: TM2011-07 (EU)
Short Name of TM: DCMA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Sensitisation
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    Submission
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    Validation
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    Peer-review
  •  
    Recommendation
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    Regulatory acceptance/Standards
CPA-I test
TM Status: Closed
Test Method Number: TM2008-11 (EU)
Short Name of TM: CPA-I test
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
In vitro sensitisation testing strategy
TM Status: Closed
Test Method Number: TM2011-14 (EU)
Short Name of TM: In vitro STS
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
  •  
    Regulatory acceptance/Standards
Valitox an alternative in vitro toxicity assay
TM Status: Closed
Test Method Number: TM2008-12 (EU)
Short Name of TM: Valitox
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Acute toxicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Zebrafish embryo acute toxicity test for acute fish toxicity testing
TM Status: Closed
Test Method Number: TM2006-01 (EU)
Short Name of TM: ZFET
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Fish acute toxicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards