TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

Note that TSAR includes only the methods that have been validated by governmental organisations affiliated with the International Cooperation on Alternative Test Methods (ICATM).

Furthermore, the documentation included in the TSAR database are the versions that were used during the validation of the respective test methods. These documents are provided for reference and transparency purposes only and may not correspond to the most up-to-date versions currently in use, nor can it be excluded that additional documentation exists. For the latest SOPs and technical information, users should contact the relevant test method developer. 

Results 101 - 105 of 146
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Porcine corneal opacity reversibility assay
TM Status: Closed
Test Method Number: TM2008-03 (EU)
Short Name of TM: PorCORA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
iPSC-derived corneal epithelial cells for ocular toxicity tests
TM Status: Closed
Test Method Number: TM2014-07 (EU)
Short Name of TM: CORNiPSC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The fluorescein leakage test method
TM Status: Closed
Test Method Number: TM2004-02 (EU)
Short Name of TM: FL
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Embryonic Stem Cell Test
TM Status: Closed
Test Method Number: TM1999-01 (EU)
Short Name of TM: EST
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Embryotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Micromass Embryotoxicity Assay
TM Status: Closed
Test Method Number: TM1999-02 (EU)
Short Name of TM: MM
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Embryotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards