TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE
TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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H2AX ICW method, gH2AX In cell western
TM Status: Closed
Test Method Number: TM2014-02 (EU)
Short Name of TM: H2AX ICW
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Genotoxicity/Mutagenicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
gH2AX/pH3 biomarkers for the prediction of DNA damage
TM Status: Closed
Test Method Number: TM2017-01 (EU)
Short Name of TM: gH2AX/pH3
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Genotoxicity/Mutagenicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Thyroid receptor microarray assay for real-time Nuclear Receptor-coregulator interaction
TM Status: Open
Test Method Number: TM2017-02 (EU)
Short Name of TM: TR MARCoNI
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
GreenScreen HC TM Genotoxicity Assay
TM Status: Closed
Test Method Number: TM2009-08 (EU)
Short Name of TM: Greenscreen
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Genotoxicity/Mutagenicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Human Reconstructed Corneal Epithelium (HCE) Eye Irritation test
TM Status: Closed
Test Method Number: TM2008-09 (EU)
Short Name of TM: SkinEthic HCE
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards