TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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Human 3-D Epidermis Model in Vitro Phototoxicity Test
TM Status: Open
Test Method Number: TM1997-02 (EU)
Short Name of TM: EpiDerm-PT
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Basal Cytotoxicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Murine Local Lymph Node Assay
TM Status: Closed
Test Method Number: TM1998-05 (US)
Short Name of TM: Murine Local Lymph Node Assay
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
IL-8 Luciferase assay for skin sensitization
TM Status: Closed
Test Method Number: TM2016-10 (JAP)
Short Name of TM: IL-8 Luciferase assay for skin sensitization
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Vitrigel-Eye Irritancy Test
TM Status: Closed
Test Method Number: TM2011-15 (JAP)
Short Name of TM: Vitrigel-Eye Irritancy Test
Responsible Organisation: JaCVAM - Japan
Topic(s): Serious eye damage/Eye irritation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Androgen Receptor TransActivation Assay using the stably transfected human AR-EcoScreen™ cell line
TM Status: Closed
Test Method Number: TM2012-07 (JAP)
Short Name of TM: AR-Ecoscreen test
Responsible Organisation: JaCVAM - Japan
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards