TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

Note that TSAR includes only the methods that have been validated by governmental organisations affiliated with the International Cooperation on Alternative Test Methods (ICATM).

Furthermore, the documentation included in the TSAR database are the versions that were used during the validation of the respective test methods. These documents are provided for reference and transparency purposes only and may not correspond to the most up-to-date versions currently in use, nor can it be excluded that additional documentation exists. For the latest SOPs and technical information, users should contact the relevant test method developer.

Results 11 - 15 of 149
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Thyroid receptor microarray assay for real-time Nuclear Receptor-coregulator interaction
TM Status: Closed
Test Method Number: TM2017-02 (EU)
Short Name of TM: TR MARCoNI
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
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    Validation
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    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Predictive testing for adverse psychiatric side effects
TM Status: Closed
Test Method Number: TM2016-01 (EU)
Short Name of TM: EDITOX
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Neurotoxicity,
Human health
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
ToxTracker Assay
TM Status: Closed
Test Method Number: TM2016-03 (EU)
Short Name of TM: ToxTracker
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Genotoxicity/Mutagenicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Thyroid method 8b: Proliferation, migration and oligodendrocyte maturation (including myelin formation) in mixed neuronal/glial culture (neurospheres) derived from human induced Pluripotent Stem Cells (hiPSC)
TM Status: Closed
Test Method Number: TM2019-18 (EU)
Short Name of TM: PMOD-hNPC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
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    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Thyroid method 7a: Measurement of intrafollicular thyroxine (T4) using zebrafish eleutheroembryos
TM Status: Closed
Test Method Number: TM2019-16 (EU)
Short Name of TM: ZETA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards