TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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In Vitro Pyrogen Test using Peripheral Blood Mononuclear Cells/IL-6
TM Status: Closed
Test Method Number: TM2002-04 (EU)
Short Name of TM: PBMC-IL6
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Pyrogenicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Threshold approach for acute fish toxicity testing
TM Status: Closed
Test Method Number: TM2005-05 (EU)
Short Name of TM: THRESH FISH
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Fish acute toxicity
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
EpiDerm™ skin corrosivity test
TM Status: Closed
Test Method Number: TM1998-03 (EU)
Short Name of TM: EpiDerm™
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin Corrosion
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
EpiSkin™ skin corrosivity test
TM Status: Closed
Test Method Number: TM1998-02 (EU)
Short Name of TM: EpiSkin™
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin Corrosion
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
In Vitro Membrane Barrier Test Method for Skin Corrosion
TM Status: Closed
Test Method Number: TM1998-01 (EU)
Short Name of TM: Corrositex®
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin Corrosion
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards