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EpiDerm™ skin corrosivity test

Topic : Skin Corrosion

Test Method Number: TM1998-03 (EU)
Short Name of TM: EpiDerm™
Year received: 1998
Responsible Organisation: EURL ECVAM - European Union '
Protocol(s)/SOP(s): 119
General Comments:

Method Description

The test method is based on the commercially available EpiDerm™ model, a reconstructed human epidermal model grown from human-derived epidermal keratinocytes which are cultured to form a multilayered and highly differentiated model of the human epidermis. The corrosivity potential of chemicals is assessed with the measurement of their citotoxic effects on EpiDerm™ model.

Track Approval Status

  • Submission
  • Validation
  • Peer-review
  • Recommendation
  • Regulatory acceptance/Standards
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