Topic: Serious eye damage/Eye irritation
Test Method Number:
TM2014-07 (EU)
Short Name of TM:
CORNiPSC
Year received:
2014
Responsible Organisation:
General Comments:
Not considered for follow-up
Method Description
The CORNiPSC is intended to be used for eye irritation testing. It is an in vitro method that applies corneal epithelial cells produced from human induced pluripotent stem cell (iPSC) lines and grown in a two-dimensional cell culture. The endpoint measurement is done by determination of cell viability.
This test method is in a presubmission stage. Further refinement of the testing protocol in the light of the addressed key endpoint, will show, if this test method could be useful in the initial step of either a Bottom-Up or a Top-Down approach to be used in an integrated testing strategy.
Track Approval Status
-
Submission
-
Validation
-
Peer-review
-
Recommendation
-
Regulatory acceptance/Standards
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