The IMOLA-IVD test method for eye irritation testing

Topic: Serious eye damage/Eye irritation

Test Method Number:

TM2010-04 (EU)

Short Name of TM:

IMOLA-IVD

Year received:

2010

Responsible Organisation:

EURL ECVAM - European Union

General Comments:

On hold-pending further information

Method Description

IMOLA-IVD is an automated platform for monitoring the vitality of living cells based on the Intelligent Mobile Lab In Vitro Diagnostics. It can detect changes in cellular metabolism after toxic exposure. It is an automatisation of the Cytosensor Microphysiometer (CM) toxicity test that was developed for the labeling of chemicals for eye corrosion/irritation and is an alternative to the Draize rabbit eye irritation test.

The IMOLA-IVD consists of three elements: (i) the sensor system, (ii) the pumping and switching of fluids, (iii) a program which runs the protocol according to the CM toxicity test protocol and collects the data.

Track Approval Status

Submission
Validation
Peer-review
Recommendation
Regulatory acceptance/Standards

Submission

Show status

Date	Stage	Comment
May 2010	Receipt of presubmission	Presubmission received.
Oct 2010	Assessment of presubmission	Submitter notified of presubmission outcome. Invitation to send a revised presubmission.
Oct 2020	Stopped	No further communication received from the submitter

Validation

Peer-review

Recommendation

Regulatory acceptance/Standards