TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

Results 1 - 5 of 141
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Epidermal Sensitization Assay
TM Status: Open
Test Method Number: TM2018-01 (JAP)
Short Name of TM: EpiSensA
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin sensitisation
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
The The VM7Luc ER TA test method: An In Vitro Assay for Identifying Human Estrogen Receptor Agonist and Antagonist Activity of Chemicals
TM Status: Open
Test Method Number: TM2016-09 (US)
Short Name of TM: VM7Luc ER TA
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Reproductive toxicity,
Endocrine disruption
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    Submission
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    Validation
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    Peer-review
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    Recommendation
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    Regulatory acceptance/Standards
Androgen Receptor Transactivation Assay for Detection of androgenic Agonist and Antagonist Activity of Chemicals using the stably transfected human 22Rv1/MMTV_GR-KO cell line
TM Status: Open
Test Method Number: TM2020-02 (OECD)
Short Name of TM: 22Rv1/MMTV_GR-KO
Responsible Organisation: OECD - International Organisation
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
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    Peer-review
  •  
    Recommendation
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    Regulatory acceptance/Standards
Thyroid method 7a: Measurement of intrafollicular thyroxine (T4) using zebrafish eleutheroembryos
TM Status: Open
Test Method Number: TM2019-16 (EU)
Short Name of TM: ZETA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
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    Submission
  •  
    Validation
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    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Thyroid method 6b: CALUX human thyroid hormone receptor beta (TRβ) reporter gene transactivation measuring agonist and antagonist activities
TM Status: Open
Test Method Number: TM2019-15 (EU)
Short Name of TM: TRβ-CALUX
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards