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Skin Sensitizer Predictor

Test Method Number: TM2013-03 (EU)
Short Name of TM: SS Predictor
Responsible Organisation: EURL ECVAM - European Union
General Comments: Not considered for follow-up
Stage of Submission: Not considered for validation
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Skinethic Skin Irritation Test-42bis

Test Method Number: TM2008-02 (EU)
Short Name of TM: SkinEthic RHE
Responsible Organisation: EURL ECVAM - European Union
General Comments: Validation finalised, OECD Test Guideline / EU Test Method available
Stage of Submission: Assessment of Pre-submission
Stage of Peer-review: Finalised
Stage of Recommendation: Published
Stage of Regulatory acceptance/Standards: Published
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

SkinEthic™ HCE Eye Irritation Test

Test Method Number: TM2015-03 (EU)
Short Name of TM: SkinEthic HCE EIT
Responsible Organisation: EURL ECVAM - European Union
General Comments: External validation performed. Report submitted for peer-review as full test submission.
Stage of Submission: Not applicable
Stage of Validation: Finalised
Stage of Peer-review: Finalised
Stage of Recommendation: Drafting
Stage of Regulatory acceptance/Standards: Revision of existing regulatory standard/guideline
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

The IMOLA-IVD test method for eye irritation testing

Test Method Number: TM2010-04 (EU)
Short Name of TM: IMOLA-IVD
Responsible Organisation: EURL ECVAM - European Union
General Comments: On hold-pending further information
Stage of Submission: Assessment of Pre-submission
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

The Irritection Assay System

Test Method Number: TM2009-01 (EU)
Short Name of TM: Ocular Irritection
Responsible Organisation: EURL ECVAM - European Union
General Comments: Revised Test Submission Template on the Ocular Irritection® test method proposed for Peer Review
Stage of Submission: Assessment Finalised
Stage of Peer-review: Finalised
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

THOR VitroDerm RhE test method for skin irritation testing

Test Method Number: TM2009-10 (EU)
Short Name of TM: VitroDerm
Responsible Organisation: EURL ECVAM - European Union
General Comments: On hold-pending further information
Stage of Submission: Assessment of Pre-submission
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Transactivation assay for detection of compounds with (anti)androgenic potential using PALM cells

Test Method Number: TM2010-02 (EU)
Short Name of TM: PALM cell assay
Responsible Organisation: EURL ECVAM - European Union
General Comments: Not prioritised for validation by ECVAM due to issues regarding the material transfer agreement
Stage of Submission: Not considered for validation
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Transactivation assay for detection of compounds with (anti)estrogenic potential using MELN cells

Test Method Number: TM2009-02 (EU)
Short Name of TM: MELN
Responsible Organisation: EURL ECVAM - European Union
General Comments: Validation stopped after consultation with test submitter
Stage of Submission: Not considered for validation
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Transcriptional activation assay for detection of androgenic activity of chemicals

Test Method Number: TM2010-07 (EU)
Short Name of TM: AR-CALUX
Responsible Organisation: EURL ECVAM - European Union
General Comments: Under validation
Stage of Submission: Assessment Finalised
Stage of Validation: Ongoing
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Transcriptomics based Genomics-Genotox assay

Test Method Number: TM2010-08 (EU)
Short Name of TM: GGA
Responsible Organisation: EURL ECVAM - European Union
General Comments: Does not qualify for entering validation
Stage of Submission: Not considered for validation
  • 1
    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards