TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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In vitro model for the prediction of respiratory sensitization of inhalable substances
TM Status: Closed
Test Method Number: TM2019-01 (EU)
Short Name of TM: ALIsens
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The cytosensor microphysiometer toxicity test
TM Status: Closed
Test Method Number: TM2004-01 (EU)
Short Name of TM: Cytosensor
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Androgen Receptor TransActivation Assay using the stably transfected human AR-EcoScreen™ cell line
TM Status: Closed
Test Method Number: TM2012-07 (JAP)
Short Name of TM: AR-Ecoscreen test
Responsible Organisation: JaCVAM - Japan
Topic(s): Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Ros (Reactive Oxygen Species) Assay for Photoreactivity
TM Status: Closed
Test Method Number: TM2013-04 (JAP)
Short Name of TM: Ros Assay
Responsible Organisation: JaCVAM - Japan
Topic(s): Skin irritation,
Skin sensitisation,
Genotoxicity/Mutagenicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Bovine corneal opacity and permeability test method
TM Status: Closed
Test Method Number: TM2003-03 (US)
Short Name of TM: BCOP
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Isolated Chicken Eye
TM Status: Closed
Test Method Number: TM2003-02 (US)
Short Name of TM: ICE
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Short Time Exposure Test
TM Status: Closed
Test Method Number: TM2008-15 (US)
Short Name of TM: STE
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Antimicrobial Cleaning Product Testing Strategy
TM Status: Closed
Test Method Number: TM2008-16 (US)
Short Name of TM: Antimicrobial Cleaning Product Testing Strategy
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Murine Local Lymph Node Assay
TM Status: Closed
Test Method Number: TM1998-05 (US)
Short Name of TM: Murine Local Lymph Node Assay
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The The VM7Luc ER TA test method: An In Vitro Assay for Identifying Human Estrogen Receptor Agonist and Antagonist Activity of Chemicals
TM Status: Closed
Test Method Number: TM2016-09 (US)
Short Name of TM: VM7Luc ER TA
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Reproductive toxicity,
Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards