|Test Method Number:||TM2010-07 (EU)|
|Short Name of TM:||AR-CALUX|
|Submission received on:||December, 2010|
|Responsible Organisation:||EURL ECVAM - European Union|
|Stage of Submission:||Assessment Finalised|
|Stage of Validation:||Ongoing|
|General Comments:||Under validation|
This method provides information on the (anti-) androgenic activity of substances when the AR-CALUX cells are exposed, leading to luminescence. The measurements and the classification model allow to predict if substances have a positive or negative reponse for either the agonist or antagonist mode of the method. This method is intended for screening purposes.
After a successful validation, this method will be part of a set of methods on basis of which a Performance Based Test Guideline for ARTAs will be developed.
|In progress||Validation||Show status|