TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.   

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3D Reconstructed Human Skin Comet assay

TM Status: Open
Test Method Number: TM2020-01 (EU)
Short Name of TM: RS Comet assay
Responsible Organisation: EURL ECVAM - European Union '
Topic(s):Genotoxicity/Mutagenicity
  • Submission
  • Validation
  • Peer-review
  • Recommendation
  • Regulatory acceptance/Standards

Human 3-D Epidermis Model in Vitro Phototoxicity Test

TM Status: Open
Test Method Number: TM1997-02 (EU)
Short Name of TM: EpiDerm-PT
Responsible Organisation: EURL ECVAM - European Union '
Topic(s):Basal Cytotoxicity
Protocol(s)/SOP(s): INVITTOX protocol
  • Submission
  • Validation
  • Peer-review
  • Recommendation
  • Regulatory acceptance/Standards

Bovine corneal opacity and permeability test method

TM Status: Closed
Test Method Number: TM2003-03 (US)
Short Name of TM: BCOP
Responsible Organisation: ICCVAM/NICEATM - United States '
Topic(s):Serious eye damage/Eye irritation
  • Submission
  • Validation
  • Peer-review
  • Recommendation
  • Regulatory acceptance/Standards

Isolated Chicken Eye

TM Status: Closed
Test Method Number: TM2003-02 (US)
Short Name of TM: ICE
Responsible Organisation: ICCVAM/NICEATM - United States '
Topic(s):Serious eye damage/Eye irritation
  • Submission
  • Validation
  • Peer-review
  • Recommendation
  • Regulatory acceptance/Standards

Short Time Exposure Test

TM Status: Closed
Test Method Number: TM2008-15 (US)
Short Name of TM: STE
Responsible Organisation: ICCVAM/NICEATM - United States '
Topic(s):Serious eye damage/Eye irritation
  • Submission
  • Validation
  • Peer-review
  • Recommendation
  • Regulatory acceptance/Standards