Dec 2014 |
Assessment finalised |
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Apr 2014 |
Finalised |
The ToxCast ER Pathway Model was reviewed by a Scientific Advisory Panel in December 2014.See <a href="https://www.epa.gov/sap/meeting-materials-december-2-4-2014-scientific-advisory-panel" target="_blank">https://www.epa.gov/sap/meeting-materials-december-2-4-2014-scientific-advisory-panel</a> for more information |
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Jun 2015 |
Finalised |
The Browne et al. 2015 publication applied a performance based validation approach to compare the results of the ToxCast ER pathway model to existing low-throughput and animal-based ER agonist assays. |
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Jun 2015 |
Published |
In a June 19, 2015 Federal Register Notice, the U.S. EPA announced that the agency is accepting ToxCast ER model data for 1812 chemicals as alternatives for EDSP Tier 1 ER binding, ER transactivation, and uterotrophic assays. More information may be found at <a href="https://www.regulations.gov/document?D=EPA-HQ-OPPT-2015-0305-0001" target="_blanl">https://www.regulations.gov/document?D=EPA-HQ-OPPT-2015-0305-0001</a> |
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Jun 2015 |
Adopted/published |
More information may be found at <a href="https://www.regulations.gov/document?D=EPA-HQ-OPPT-2015-0305-0001" target="_blank">https://www.regulations.gov/document?D=EPA-HQ-OPPT-2015-0305-0001</a> |
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