Topic: Serious eye damage/Eye irritation
Test Method Number:
TM2011-15 (JAP)
Short Name of TM:
Vitrigel-Eye Irritancy Test
Year received:
2011
Responsible Organisation:
JaCVAM - Japan
General Comments:
Method Description
The Vitrigel-Eye Irritancy Test (EIT) method is an in vitro test method that allows the identification of test chemicals not requiring classification and labelling for eye irritation or serious eye damage (GHS No Category) as defined by the UN GHS without further testing. This method assesses the eye irritation potential of a test chemical based on its ability to induce damage to the barrier function of the human corneal epithelium (hCE) models. In this test method, time-dependent changes in the Transepithelial Electrical Resistance (TEER) values are indicative of damage to the barrier function of the corneal epithelium following exposure to a test chemical.
Track Approval Status
-
Submission
-
Validation
-
Peer-review
-
Recommendation
-
Regulatory acceptance/Standards
| Step | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Submission | Show status | ||||||||
|
|||||||||
| Validation | Show status | ||||||||
|
|||||||||
| Peer-review | Show status | ||||||||
|
|||||||||
| Recommendation | Show status | ||||||||
|
|||||||||
| Regulatory acceptance/Standards | Show status | ||||||||
|
|||||||||