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Results: 31 - 40 of 66

The Electrophilic Allergen Screening Assay for the Detection of Substances Causing Allergic Contact Dermatitis

Test Method Number: TM2016-01 (US)
Short Name of TM: EASA
Topic(s): Skin sensitisation
Responsible Organisation: ICCVAM/NICEATM - United States
Stage of Submission: Assessment Finalised
Stage of Validation: Planning
  • 1
    Submission
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    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Yeast Estrogen and Yeast Androgen Screening Assays

Test Method Number: TM2011-03 (EU)
Short Name of TM: YES / YAS
Topic(s): Reproductive toxicity - Endocrine disruption
Responsible Organisation: EURL ECVAM - European Union
General Comments: After prioritization, only the YAS assay was submitted as a full submission, after an external validation.
Stage of Submission: Assessment Finalised
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    Submission
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    Validation
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    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Valitox an alternative in vitro toxicity assay

Test Method Number: TM2008-12 (EU)
Short Name of TM: Valitox
Topic(s): Acute toxicity
Responsible Organisation: EURL ECVAM - European Union
General Comments: This method was later officially submitted as DAP (Dequenching after photobleaching cytotoxicity test). See TM2011-01
Stage of Submission: Not considered for validation
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    Submission
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    Validation
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    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Two-tiered approach to determine the skin sensitising capacity and potency of chemicals

Test Method Number: TM2011-12 (EU)
Short Name of TM: 2-TA
Topic(s): Sensitisation
Responsible Organisation: EURL ECVAM - European Union
General Comments: Submission closed because an improved version of the test method has been submitted under TM2012-05
Stage of Submission: Not considered for validation
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    Submission
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    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Skinethic Skin Irritation Test-42bis

Test Method Number: TM2008-02 (EU)
Short Name of TM: SkinEthic RHE
Topic(s): Skin irritation
Responsible Organisation: EURL ECVAM - European Union
General Comments: Validation finalised, OECD Test Guideline / EU Test Method available
Stage of Submission: Assessment of Pre-submission
Stage of Peer-review: Finalised
Stage of Recommendation: Published
Stage of Regulatory acceptance/Standards: Published
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    Submission
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    Validation
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    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Human Reconstructed Corneal Epithelium (HCE) Eye Irritation test

Test Method Number: TM2008-09 (EU)
Short Name of TM: SkinEthic HCE
Topic(s): Eye irritation
Responsible Organisation: EURL ECVAM - European Union
General Comments: This test method was unable to comply fully with the acceptance criteria set by the validation management group. A revised SkinEthicâ„¢ HCE EIT test method was re-submitted for assessment by EURL ECVAM and formal ESAC peer review in October 2015 (See TM2015-03, SkinEthic-HCE-EIT).
Stage of Submission: Not considered for validation
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    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Skin Sensitizer Predictor

Test Method Number: TM2013-03 (EU)
Short Name of TM: SS Predictor
Topic(s): Skin sensitisation
Responsible Organisation: EURL ECVAM - European Union
General Comments: Not considered for follow-up
Stage of Submission: Not considered for validation
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    Submission
  • 2
    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

Skin PAMPA Permeability System

Test Method Number: TM2012-02 (EU)
Short Name of TM: Skin PAMPA
Topic(s): Skin permeability/penetration
Responsible Organisation: EURL ECVAM - European Union
General Comments: Validation on hold. Considered to be followed up in the wider context of ADME methods
Stage of Submission: Assessment of Full submission
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    Submission
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    Validation
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    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

SENS-IS

Test Method Number: TM2011-11 (EU)
Short Name of TM: SENS-IS
Topic(s): Skin sensitisation
Responsible Organisation: EURL ECVAM - European Union
General Comments: Under external validation
Stage of Submission: Assessment Finalised
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    Submission
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    Validation
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    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards

RHE IL-18 potency test for skin sensitization

Test Method Number: TM2012-05 (EU)
Short Name of TM: RHE IL-18
Topic(s): Skin sensitisation
Responsible Organisation: EURL ECVAM - European Union
General Comments: Invitation to send a full submission
Stage of Submission: Assessment of Pre-submission
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    Submission
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    Validation
  • 3
    Peer-review
  • 4
    Recommendation
  • 5
    Regulatory acceptance/Standards