TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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Skin Sensitizer Predictor
TM Status: Closed
Test Method Number: TM2013-03 (EU)
Short Name of TM: SS Predictor
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Porcine corneal opacity reversibility assay
TM Status: Closed
Test Method Number: TM2008-03 (EU)
Short Name of TM: PorCORA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
iPSC-derived corneal epithelial cells for ocular toxicity tests
TM Status: Closed
Test Method Number: TM2014-07 (EU)
Short Name of TM: CORNiPSC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The fluorescein leakage test method
TM Status: Closed
Test Method Number: TM2004-02 (EU)
Short Name of TM: FL
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Embryonic Stem Cell Test
TM Status: Closed
Test Method Number: TM1999-01 (EU)
Short Name of TM: EST
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Embryotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Micromass Embryotoxicity Assay
TM Status: Closed
Test Method Number: TM1999-02 (EU)
Short Name of TM: MM
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Embryotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Postimplantation Rat Whole-Embryo Culture Assay
TM Status: Closed
Test Method Number: TM1999-03 (EU)
Short Name of TM: WEC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Embryotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Transactivation assay for detection of compounds with (anti)estrogenic potential using MELN cells
TM Status: Closed
Test Method Number: TM2009-02 (EU)
Short Name of TM: MELN
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Predictive testing for adverse psychiatric side effects
TM Status: Open
Test Method Number: TM2016-01 (EU)
Short Name of TM: EDITOX
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Neurotoxicity,
Human health
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
epiCS Skin Irritation Test
TM Status: Closed
Test Method Number: TM2009-09 (EU)
Short Name of TM: epiCS SIT
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards