TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

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Ashland Skin Irritation Test
TM Status: Closed
Test Method Number: TM2015-02 (EU)
Short Name of TM: Ashland RhE SIT
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Red Blood Cell haemolysis
TM Status: Closed
Test Method Number: TM2004-04 (EU)
Short Name of TM: RBC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Neutral Red Release Assay
TM Status: Closed
Test Method Number: TM2004-03 (EU)
Short Name of TM: NRR
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Myeloid U937 Skin Sensitisation Test
TM Status: Closed
Test Method Number: TM2009-05 (EU)
Short Name of TM: MUSST
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Prediction of the in vivo estrogenic activity of chemicals ERalpha-CALUX
TM Status: Closed
Test Method Number: TM2009-11 (EU)
Short Name of TM: ERalpha-CALUX
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The cytosensor microphysiometer toxicity test
TM Status: Closed
Test Method Number: TM2004-01 (EU)
Short Name of TM: Cytosensor
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
In vitro approach for organophosphorous compounds-induced neurotoxicity (OP Neurotox Assay)
TM Status: Closed
Test Method Number: TM2009-12 (EU)
Short Name of TM: OPIV
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Neurotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Embryonic Rat Dorsal Root Ganglia Organotypic Culture
TM Status: Closed
Test Method Number: TM2010-06 (EU)
Short Name of TM: DRG
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Neurotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
devTOX qp (Stemina) devTOX quick Predict
TM Status: Closed
Test Method Number: TM2014-04 (EU)
Short Name of TM: devTOXqP
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Teratogenicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Skin PAMPA Permeability System
TM Status: Closed
Test Method Number: TM2012-02 (EU)
Short Name of TM: Skin PAMPA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin permeability/penetration
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards