TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

Results 41 - 50 of 140
Download (Excel compatible)
Thyroid method 2b: Thyroperoxidase (TPO) inhibition based on oxidation of Luminol
TM Status: Open
Test Method Number: TM2019-05 (EU)
Short Name of TM: TPO-LUM
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Thyroid method 8b: Proliferation, migration and oligodendrocyte maturation (including myelin formation) in mixed neuronal/glial culture (neurospheres) derived from human induced Pluripotent Stem Cells (hiPSC)
TM Status: Open
Test Method Number: TM2019-18 (EU)
Short Name of TM: PMOD-hNPC
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
In vitro model for the prediction of respiratory sensitization of inhalable substances
TM Status: Closed
Test Method Number: TM2019-01 (EU)
Short Name of TM: ALIsens
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Two-tiered approach to determine the skin sensitising capacity and potency of chemicals
TM Status: Closed
Test Method Number: TM2011-12 (EU)
Short Name of TM: 2-TA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
In vitro BALB/c 3T3 Cell Transformation Assay
TM Status: Closed
Test Method Number: TM2004-07 (EU)
Short Name of TM: BALB/c 3T3 CTA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Carcinogenicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The Colony Forming Unit-Granulocyte/Macrophage Assay for predicting acute neutropenia in humans
TM Status: Closed
Test Method Number: TM2000-01 (EU)
Short Name of TM: CFU-GM
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Acute toxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Automated screening to detect cardiotoxicity in zebrafish
TM Status: Closed
Test Method Number: TM2009-07 (EU)
Short Name of TM: Zebrafish assay
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Cardiotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Rat skin transcutaneous electrical resistance test
TM Status: Closed
Test Method Number: TM1995-01 (EU)
Short Name of TM: TER
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin Corrosion
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Chorioallantoic membrane vascular assay
TM Status: Closed
Test Method Number: TM2008-06 (EU)
Short Name of TM: CAMVA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The IMOLA-IVD test method for eye irritation testing
TM Status: Open
Test Method Number: TM2010-04 (EU)
Short Name of TM: IMOLA-IVD
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards