TRACKING SYSTEM FOR ALTERNATIVE METHODS TOWARDS REGULATORY ACCEPTANCE

TSAR indicates the stages methods have reached in terms of acceptance as a recognised test method for use in various sectors together with a summary description. Where available, TSAR also includes relevant records and documents associated with a method linked to the different steps of the entire process: submission, validation, peer-review, recommendations and regulatory acceptance including international standards represented in the tracking system.

Results 131 - 140 of 140
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Genomic Embryonic Stem cell Test method
TM Status: Closed
Test Method Number: TM2012-04 (EU)
Short Name of TM: gEST
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Reproductive toxicity,
Embryotoxicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Cell Transformation Assay Based on the Bhas 42 Cell Line
TM Status: Closed
Test Method Number: TM2012-06 (EU)
Short Name of TM: Bhas 42 CTA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Carcinogenicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Syrian hamster embryo cell transformation assay at pH 6.7
TM Status: Closed
Test Method Number: TM2005-02 (EU)
Short Name of TM: SHE 6.7 CTA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Carcinogenicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Syrian hamster embryo cell transformation assay at pH 7.0
TM Status: Closed
Test Method Number: TM2005-03 (EU)
Short Name of TM: SHE 7.0 CTA
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Carcinogenicity
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Human Cell Line Activation Test
TM Status: Closed
Test Method Number: TM2008-05 (EU)
Short Name of TM: hCLAT
Responsible Organisation: EURL ECVAM - European Union 
Topic(s): Skin sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
A new in vitro eye irritation test with a 3D-reconstructed human cornea epithelium, MCTT HCE™
TM Status: Open
Test Method Number: TM2016-04 (KOR)
Short Name of TM: MCTT HCE™-EIT
Responsible Organisation: KoCVAM - Republic of Korea
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Hen’s Egg Test – Chorio-Allantoic Membrane
TM Status: Open
Test Method Number: TM2016-05 (BRA)
Short Name of TM: HET-CAM
Responsible Organisation: BraCVAM - Brazil 
Topic(s): Serious eye damage/Eye irritation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
Monocyte Activation Test
TM Status: Open
Test Method Number: TM2016-06 (BRA)
Short Name of TM: MAT
Responsible Organisation: BraCVAM - Brazil 
Topic(s): Quality control of vaccines,
Airborne pyrogens
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The Electrophilic Allergen Screening Assay for the Detection of Substances Causing Allergic Contact Dermatitis
TM Status: Open
Test Method Number: TM2016-07 (US)
Short Name of TM: EASA
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Skin sensitisation
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards
The ToxCast Estrogen Receptor Agonist Pathway Model
TM Status: Closed
Test Method Number: TM2016-08 (US)
Short Name of TM: ToxCast ER Pathway Model
Responsible Organisation: ICCVAM/NICEATM - United States 
Topic(s): Reproductive toxicity,
Endocrine disruption
  •  
    Submission
  •  
    Validation
  •  
    Peer-review
  •  
    Recommendation
  •  
    Regulatory acceptance/Standards