|Test Method Number:||TM2009-07 (EU)|
|Short Name of TM:||Zebrafish assay|
|Submission received on:||Thursday, July 9, 2009|
|Responsible Organisation:||EURL ECVAM - European Union|
|Stage of Submission:||Assessment of Pre-submission|
|General Comments:||On hold-pending further information|
The aim of the method is to identify compounds that induce arrhythmia and consequently present a potential risk of QT interval prolongation. In addition, compounds that induce non zERG-related cardiotoxicity should be identified, to be classified as generally cardiotoxic.
The test is inteneded as screening method to detect cardiotoxicity of products in early stages of drug development.
|In progress||Submission||Show status|