TSAR (Tracking System for Alternative test methods Review Validation and Approval in the Context of EU Regulations on Chemicals).

European Commission JRC IHCP TSAR

TSAR : Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals

+ Review and Validation

Method submission

Regulatory relevance assessment

Validation statement

Post-validation

+ Regulatory Approval

Stage 1: Technical Discussions with EU Experts

Stage 2: Technical conclusion and proposal agreement

Stage 3: Draft Proposal consultation

Stage 4: Final Proposal and adoption

Validation of Methods

Approval of Methods

+ Skin irritation and Corrosion

TER - Corrosion

HSM - Corrosion

CORROSITEX - Corrosion

EPISKIN - Irritation

EPIDERM - Irritation

Modified EpiDerm

+ Eye Irritation

+ Skin Sensitisation

+ Acute Systemic Toxicity

Acute Inhalation Toxicity

+ Repeated Dose Toxicity

+ Reproductive Toxicity

3T3NRU Phototoxicity

Skin absorption

+ Acute Toxicity to Fish

Validation of Methods

Currently this section is being updated, in the meantime, for additional information on the IHCP activities regarding the validation of alternative methods, please consult the web site of European Centre for the Validation of Alternative Methods (ECVAM).