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| TSAR : Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals |
| Other |
| ABSORPTION THROUGH SKIN - B.45 In vitro Skin Absorption |
| 3 Rs Category | : | Replacement |
| Type of Method | : | In vitro |
| Validation Statement | : | None |
| Comment | : | Does not fully replace the in vivo test in all cases |
| Status of adoption in EU | : | Adopted in 2008. |
| 1st Published in EC Regulations/ Updates | : | Regulation 440/2008/EC (Official Journal L 142 2008) |
| Reconducted to TMR (updated when appropriate) | : | Regulation 440/2008/EC (Official Journal L 142 2008) |
| Text of EU method | : | B.45 |
| Corresponding OECD TG | : | TG 428 |
| Status of adoption by OECD | : | OECD |
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