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| TSAR : Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals |
| Eye Irritation |
Hen's egg test - chorio-allantoic membrane (HET-CAM test). HET-CAM |
| 3 Rs Category | : | Partial Replacement |
| Type of Method | : | In vitro |
Statement on scientific validity and potential use | : | ESAC (27/04/2007) recommended further work before validity can be fully assessed. |
| Comment | : | Referenced in REACH Guidance on "Information Requirements and Chemical Safety Assessment" (May 2008) ECHA |
| Status of adoption in EU | : | Positive results already accepted since 2002: See in Manual of Decisions of the Competent Authorities MoD. Formal adoption to be considered when additional information will be available. |
| Corresponding OECD TG | : | None |
| Status of OECD adoption | : | Not included and not foreseen yet. No OECD activity. |
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