TSAR : Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals

Eye Irritation
Low Volume Eye Test (LVET)
3 Rs Category :  Refinement/Reduction
Type of Method :  In vivo
Validation Statement :  Scientific validity of test method (ESAC): 09/07/2009.
Comment :  The test method was not recommended for prospective use, i.e. to generate new data.
ESAC acknowledged that existing data on household detergents and cleaning products as well as their main ingredient class, i.e. surfactants as used in these products, may be useful in the context of classification and labelling decisions as outlined in the CLP regulation (1272/2008/EC) and in particular within weight of evidence approaches, as well as to support the validation of alternative methods.
No additional testing should be performed to further develop or validate this method.
Status of adoption in EU :  Not included in EU regulation.
Corresponding OECD TG :  None
Status of adoption by OECD :  Not included and not foreseen yet.
No OECD activity.